ABSTRACT
A significant reduction in intestinal and caecal colonization of Clostridium perfringens [C. perfringens] during 21 days post infection [PI] has occurred on using the probiotics Pediococcus acidilactici or Saccharomyces boiilardii. However; the former resulted in a higher reduction than the latter. The same results were also obtained with Saccharomyces boulardii at 7 and 14 days PI. Reduction in Salmonella typhimurium [S. typhinwrium] caecal colonization significantly happened during the entire period of the experiment [21 days] on using the two studied probiotics. Neither mortality nor disease lesions could be obtained in experimentally infected groups with the used doses of both S.typhimurium and C perfringens under the conditions of the experiment
Subject(s)
Animals , Clostridium perfringens , Salmonella typhimurium , Probiotics , Pediococcus , Saccharomyces , Intestines , Bacterial Infections , ChickensABSTRACT
For assaying the immunomodulatory effect of the studied synbiotic "Enterococcus faecium and oligosaccharides" the humoral immune response, the cell mediated immune response, the major lymphoid organs / body weight indices and the histomorphological changes of the major lymoid organs were determined in non-immunosuppressed and immunosuppressed broiler chickens with cyclophosphamide [CP]. Statistical significant immunopotentiation in both humoral immunity and cell mediated immunity was obtained. Significant increases in bursa / body weight, spleen / body weight and thymus / body weight indices were also obtained. Histomorphological changes in bursa of Fabricius showed many activated lymphoblasts and reticular cell hyperplasia in the medula of the bursal follicles as compared with their controls. In conclusion; the use of the studied synbiotic can positively regulate or alter the immune response not only in normal broiler chickens but also in the immuno-compromised as well